Exploring RNA Structural Codes with SHAPE Chemistry
نویسندگان
چکیده
منابع مشابه
Structural Chemistry of Human RNA Methyltransferases.
RNA methyltransferases (RNMTs) play important roles in RNA stability, splicing, and epigenetic mechanisms. They constitute a promising target class that is underexplored by the medicinal chemistry community. Information of relevance to drug design can be extracted from the rich structural coverage of human RNMTs. In this work, the structural chemistry of this protein family is analyzed in depth...
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متن کاملStructural Chemistry
▶ Offers original research papers on condensed and gaseous states of matter ▶ Spans artificial divisions in current literature among the areas of structure determination, energetics, and applications ▶ Offers broad discussion of results, observation of relationships among various properties, and applications of structure and energy information in all domains of chemistry ▶ 97% of authors who an...
متن کاملStructural Chemistry
▶ Offers original research papers on condensed and gaseous states of matter ▶ Spans artificial divisions in current literature among the areas of structure determination, energetics, and applications ▶ Offers broad discussion of results, observation of relationships among various properties, and applications of structure and energy information in all domains of chemistry ▶ 97% of authors who an...
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ژورنال
عنوان ژورنال: Accounts of Chemical Research
سال: 2011
ISSN: 0001-4842,1520-4898
DOI: 10.1021/ar200051h